UST is a private Roman Catholic University run by the Order of Preachers in Manila. It is the only Pontifical University in Asia. It is the only university (Catholic or not) to have been visited by two popes three times, twice by Pope John Paul II in 1981 and 1995 and once by Pope Paul VI in 1970 (I was in second year high school then).
It was built in a 215,000 sq. meter campus in Sampaloc, Manila. The university was originally located within the walled city of Intramuros, Manila.